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Selected Publications

Feala J. D., Cortes J., Duxbury P.M., McCulloch A.D, Piermarocchi C., Paternostro G.: Statistical Properties and Robustness of Biological Controller-Target Networks. PLoS ONE 7(1): e29374. doi:10.1371/journal.pone.0029374 2012

Tiziani S., Kang Y., Choi J. S., Roberts W., Paternostro G.: Metabolomic high-content nuclear magnetic resonance-based drug screening of a library of kinase inhibitors Nature Communications, 2 : 545 doi:10.1038/ncomms1562 2011

Feala J. D., Cortes J., Duxbury P.M., Piermarocchi C., McCulloch A.D., Paternostro G.: Systems approaches and algorithms for discovery of combinatorial therapies WIREs Syst Biol Med, 2:181-193 2010

Feala JD, Coquin L, Zhou D, Haddad GG, Paternostro G, McCulloch AD.: Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis. BMC Syst Biol. 2009 Sep 9;3:91 BMC Systems Biology

Calzolari D., Bruschi S., Coquin L., Schofield J., Feala J. D., Reed J.C., McCulloch A.D., Paternostro G.: Search algorithms as a framework for the optimization of drug combinations. PLoS Comp Biol 4(12):1-14, 2008 PLoS CB

Coquin L., Feala J. D., McCulloch A.D., Paternostro G.: Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue. Molecular Systems Biology, 4:233:1-13, 2008 Nature MSB

Bruschi S. Calzolari D., Coquin L., Paternostro G.: HORA suite: A database and software for human metabolomics. Metabolomics, 4:90-93, 2008 Springer

Calzolari D., Paternostro G. , Harrington Jr. P. L., Piermarocchi, C., Duxbury P. M. Selective control of the apoptosis signaling network in heterogeneous cell populations. PlosOne, Jun 20:2:e547, 2007 Plos

Feala J. D., Coquin L., McCulloch A.D., Paternostro G.: Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis. Molecular Systems Biology, 3:99 :1-7, 2007 Nature MSB

Ferrarini, L., Bertelli, L., Feala, J., McCulloch, A.D., Paternostro, G.: A more efficient search strategy for aging genes based on connectivity. Bioinformatics, 21:338-348, 2005. PubMed Oxford Journals

Paternostro, G., Vignola, C., Bartsch, D-U., Omens, J.H., McCulloch, A.D., Reed, J.C.: Age-associated cardiac dysfunction in Drosophila melangaster. Circ Res, 88:1053-1058, 2001 PubMed Circ Res

Reed, J., Paternostro, G.: Post-mitochondrial regulation of apoptosis during heart failure. Proc Natl Acad Sci, USA, 96:7614-7616, 1999 PubMed PNAS

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